Total number of patients recruited: 398 TARGET ACHIEVED!

Enter patients into the trial database here

The OSAC trial database must only be accessed from computers supported by an OSAC collaborating institution (University or GP Practice), on the host organisation premises. For all permissions queries contact the Bristol trial team.

Information for clinicians


You can download the current study protocol by clicking here.

Inclusion and exclusion criteria

A summary of the study eligibility and exclusion criteria can be downloaded by clicking here.

Ideas for successful recruitment

You can find suggestions from successfully recruiting GP practices, about factors that enable OSAC trial recruitment, by clicking here.

Trial Flow Diagram

A summary of the trial processes can be downloaded here.

Trial Documents

Here you can access local versions of study documents (select your local study centre). If the document you need is not listed, please contact your local study team.

Trial poster click here
Consent form Please contact the trial team
Consent to contact form
(must be used for any home recruitment visits)
Please contact the trial team
Full patient information booklet click here
Summary patient information sheet click here
Screening log click here
SAE reporting form click here
SAE reporting procedure click here
Withdrawal form click here
Patient Symptom Diary (for information only) click here
3 month primary care medical notes review form (for information only) click here

OSAC trial Case Report Form (CRF)

If you run out of paper versions of the trial Case Report Form documents, in the first instance contact your local study team. In an emergency, authorised recruiting staff can print additional copies using the links below.

Case Report Form Section 1:
Face-to-Face Patient Eligibility Check
Section 2:
Clinical Examination and Diagnosis
Section 3:
Participant Registration
Section 4:
Symptoms, Signs and Medical History

Database Access Instructions

Click here for instructions on how to start off the process of entering data into the online database, including use of the online Screening ID.

Patient packs

To re-order more patient packs, please download the OSAC requisition and transfer form and fax to your local co-ordinating centre.

Clinical Contacts

If you have a clinical query relating to the management of a patient recruited into the OSAC trial, you can contact the trial Principal Investigators here.

Contact the study team

For any other query relating to the OSAC trial, please contact your local trial team.

More about OSAC

Funding / sponsorship

The OSAC trial is funded by a grant of £871,958 from the Department of Health's National Institute for Health Research (NIHR) National School for Primary Care Research.

The OSAC trial is sponsored by the University of Bristol.

Safety monitoring

The safety of patients enrolled onto the OSAC trial is monitored by the University Hospitals Bristol NHS Foundation Trust.

Study Steering Committee

The OSAC trial is governed by an independent Steering Committee. For information about the work and membership of the Committee please contact the Trial Manager, Harriet Downing, tel: 0117 331 3906 / e-mail: harriet.downing@bristol.ac.uk.


A graph of current recruitment against target will be available here from September 2013.

Training opportunities

The OSAC trial team provides training for all recruiting GP sites, and can put you in touch with providers of other relevant training e.g. ICH-GCP. For further information about ICH - GCP training please contact your local PCRN.